European Journal of Medical and Health Sciences 2024-07-15T10:40:43-04:00 Editor-in-Chief Open Journal Systems European Journal of Medical and Health Sciences High C-Reactive Protein Serum Levels as a Risk Factor for Preeclampsia 2024-07-15T10:40:43-04:00 Anak Agung Ngurah Jaya Kusuma I Made Darmayasa Endang Sri Widiyanti I Gede Bagus Arya Maharta <p><span class="fontstyle0"><em>Introduction</em>: </span><span class="fontstyle2">Preeclampsia is a hypertensive syndrome in pregnancy characterized by increased blood pressure, proteinuria, and complications such as liver dysfunction and visual impairment. This condition is associated with an inflammatory reaction and failure of trophoblast invasion of maternal arteries, which involves an increase in proinflammatory cytokines that indirectly induce CRP production. However, data showing the value of CRP levels as an indicator of the incidence of preeclampsia in Indonesia is minimal. This study aims to evaluate CRP levels as a predictor of preeclampsia.<br /></span><span class="fontstyle0"><em>Methods</em>: </span><span class="fontstyle2">This case-control study involved pregnant women with preeclampsia and normal pregnant women who went to the Obstetric Emergency Installation at Prof. Hospital. Dr. I.G.N.G Ngoerah Denpasar. All data were obtained from patient medical records and then analyzed using the SPSS v.22.<br /></span><span class="fontstyle0"><em>Results</em>: </span><span class="fontstyle2">This study involved 56 pregnant women consisting of 28 normotensive pregnant women (control) and 28 pregnant women with preeclampsia (cases) at Prof. Dr. I.G.N.G. Ngoerah General Hospital Denpasar from January to December 2023. The median age was 27.5 years (control) and 26.0 years (cases), with an age range of 18–40 years. The median BMI WAS 21.65 kg/m</span><span class="fontstyle2">2 </span><span class="fontstyle2">(controls) and 21.80 kg/m</span><span class="fontstyle2">2 </span><span class="fontstyle2">(cases). Most patients in both groups were nulliparous (50.0%, controls; 42.9%, cases). Based on ROC analysis, the CRP cut-off value of 7.76 mg/dL has a sensitivity of 76.7%, specificity of 78.6%, and an area under the curve (AUC) of 0.737, where pregnant women with high CRP (</span><span class="fontstyle3">≥</span><span class="fontstyle2">7.76 mg/dL) had a 12.048-fold higher risk (95%CI 3.496–41.515; p </span><span class="fontstyle4">&lt; </span><span class="fontstyle2">0.001) of experiencing preeclampsia compared to pregnant women with low CRP levels.<br /></span><span class="fontstyle0"><em>Conclusion</em>: </span><span class="fontstyle2">High serum CRP levels are a risk factor for preeclampsia. These findings indicate that measuring CRP levels can be a potential tool for identifying the risk of preeclampsia in the pregnant population.</span> </p> 2024-07-12T00:00:00-04:00 Copyright (c) 2024 Anak Agung Ngurah Jaya Kusuma, I Made Darmayasa, Endang Sri Widiyanti, I Gede Bagus Arya Maharta Demographical Study of Appendicitis Patients in Basra/Iraq 2024-07-11T10:40:41-04:00 Zainab Nihad Shaker Dawood Salman Mahdi Ihsan Edan Alsaimary <div id="folder32" class="folder"> <div class="opened"> <div class="line"><em>Background. </em>Acute appendicitis is a prevalent cause of severe lower abdomen discomfort that necessitates rapid attendance at the emergency department, it occurs in approximately 17,700,000 individuals worldwide each year. <em>Method. </em>A case-control investigation was carried out on the patients with appendicitis in the operating room at Al-Sadr Hospital and Al-Shifaa Teaching Hospital in Basra, and the control group was randomly selected. Information was collected using a questionnaire. <em>Results and Discussion. </em>T<span style="font-size: 0.875rem;">his study’s appendicitis patients were 56 males and 44 females. The age group ranging from 10 to 25 years was the most group affected by appendicitis (63%). The rate of non-smoking patients was 69%, higher than that of smoking patients (31%) and higher than smoking control (17%), with significance. The patients who live in the center have a high rate when compared with patients who live in the peripheral. The rate of patients who had a family history of appendicitis was (34%) lower than that of patients who had not a family history. Still, when compared with control with a family history (15%), their rate was higher with significance. <em>Conclusion.</em> The results of our study conclude that appendicitis affects young ages, but it can occur at any age, and a slight predominance can be observed in males compared to females, without significance. Smoking and a positive family history of appendicitis can be factors leading to appendicitis in an individual.</span></div> </div> </div> 2024-07-08T00:00:00-04:00 Copyright (c) 2024 Zainab Nihad Shaker, Dawood Salman Mahdi, Ihsan Edan Alsaimary Diagnosis and Management of Labor Dystocia According to the Friedman Curve 2024-06-09T08:58:46-04:00 I Gde Sastra Winata Tjokorda Istri Agung Devitia Widya Paramita Putri Anak Agung Ayu Vidya Pradnyandari <p><strong>Introduction: </strong>Labor dystocia or abnormal prolonged delivery is one of the common indications regarding unplanned cesarean deliveries. A better understanding of the diagnosis and management of labor dystocia according to friedman curve could lead to new opportunities to increase the rate of vaginal delivery. This paper aims to summarize known diagnosis and management techniques according to the Friedman curve. <strong>Method: </strong>Literature reviews were compiled based on article obtained using search engine “Google Scholar” and “PubMed” with keywords “Diagnosis", “Friedman Curve”, “Labor”, “Dystocia” and “Management”. There were 10 articles that were appropriate for this purpose. <strong>Result and discussion: </strong>Labor dystocia is a labor complication where the labor process is abnormally slow or prolonged, hence the term abnormal prolonged labor. This involves a variety of problem which is abbreviated by three P’s, Power, Passage and Passenger. Power is defined by the ability of the uterus to contract during labor. Passage is defined as divergence between the measurements of the fetal head and the maternal pelvis that might be caused by ineffective uterine contraction or macrosomic fetus, so that result in obstructed labor. Passenger is defined as the presentation, position and fetal development that might influence the dystocia incident. Labor dystocia is one of the common indication regarding unplanned caesarian deliveries. Therefore, early diagnosis and management of labor dystocia is crucial in improving outcome in labor dystocia patients, both for the mother and the newborn. <strong>Conclusion: </strong>Labor is influenced by multiple factors related to the mother and fetus. The theories of Friedman and recent advancements have significantly impacted the diagnosis of protraction or arrest disorder. In challenging situations, timely identification and suitable management are crucial. Educating patients about labor preparation is vital to prevent adverse conditions that can lead to complications and even mortality for both mother and fetus.</p> 2024-07-08T00:00:00-04:00 Copyright (c) 2024 I Gde Sastra Winata, Tjokorda Istri Agung Devitia Widya Paramita Putri, Anak Agung Ayu Vidya Pradnyandari